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Given that the proposed HbA1c diagnostic for screening are both insensitive and racially discrepant, what is the optimal way to screen for diabetes? Dr. Rhee recommended that doctors perform the standard 75 gram OGTT, or, at the very least, a fasting glucose level followed by the OGTT in individuals whose levels are abnormal (100 mg/dL and above).
It is a synthetic 17-lactone drug that is a renal competitive aldosterone antagonist in a class of pharmaceuticals called potassium-sparing diuretics, used primarily to treat heart failure, ascites in patients with liver disease, low-renin hypertension, hypokalemia, secondary hyperaldosteronism (such as occurs with hepatic cirrhosis), and Conn's syndrome (primary hyperaldosteronism).

 

Dr. Rhee and colleagues compared the identification of prediabetes, dysglycemia (diabetes or prediabetes), and diabetes by the recommended HbA1c-based screening with the conventional oral glucose tolerance test (OGTT).
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